BHT-3021 is the safety and tolerability, proved without an increase in adverse events compared with placebo. Preliminary data from the 1 mg dose cohort indicate that treatment with BHT-3021 may cause beta cell preservation as well as the induction of immune tolerance to pancreatic autoantigens. – – Clinical Trial criteria Key inclusion criteria for this study were: a diagnosis of type 1a diabetes mellitus on ADA criteria, 5 years has T1D T1D, 18 years, 40 years at diagnosis of type 1 diabetes, detectable fasting C-peptide level, increasing C-peptide screening during mixed meal tolerance test, and presence of antibodies to at least one beta-cell antigen .
Is a disease that company’s product candidates, the immune system to its normal state are known as restore ‘tolerance ‘by selectively eliminating specific adverse immune reactions, while the rest of the immune system intact. The company has two lead product in clinical trials based on BHT – DNA, which the Company believes have demonstrated safety and tolerability. Beside preliminary efficacy The first product candidate, BHT-3009 was the subject of a completed Phase II clinical trial for MS. The second product candidate, BHT-3021, is currently in a Phase I / II clinical trial for type 1 diabetes . More information about Bayhill Therapeutics is available at..Whom this study this study of which authors indicate that physicians and patient, especially the elderly should considered the knowledge this study on adverse effects along with other information on risks and benefits of testosterone treatment. Also note that more research is required to safety issues issues of security points raised through this study.. The report in New England Journal of Medicine delivers detailed data on the outcome and undesirable events among participants.
The authors caution that the capacity for drag additional conclusions about the safety to the testosterone therapy is on these findings on various factors, including the small size of this degree, chronic and the fact the study population of was older and higher rates of illnesses is regions and mobility impairment as individuals living within most other studies.