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Understanding howosomes never tie their shoelacesIn the current issue of the journal Nature, Miguel Godinho Ferreira lead, Principal Investigator at the Instituto Gulbenkian de Ci ncia in Portugal, a team of researchers in order a paradox a paradox has puzzled biologists since the discovery of telomeres, the protective tips of chromosomes are generated while broken chromosome ends by DNA damage are together together, telomeres are never connected to each other, allowing for the proper separation of the genetic material in all cells in our bodies. Since telomeres erode in response to the continuous cell divisions in our body, this protective function fades away as we get older. Complete loss of telomeres leads sticky chromosome – ends that come together to create the chaos genetic very initial steps of of cancer. Understanding how the tips of the chromosomes from DNA repair and how the cells react are protected if they are unprotected provide insights into the initial stages of tumourgenesis, Aging and future therapeutic interventions.


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